*Covid-19 Alert - We are closing one hour early monday - saturday.*
Serving Hilton Head Island, Bluffton, & Beaufort County South Carolina
Burke’s Main Street Pharmacy is here to help both local residents and visitors to Hilton Head Island look and feel their best. Our certified pharmacists are ready to help with your pharmacy and compounding needs. We can also help you find the medical equipment you need for daily life or to ensure your vacation to Hilton Head Island is the best it can be.