• Welcome to Burke's Main Street Pharmacy!

    Our friendly staff is excited to serve you.,Our friendly staff is excited to serve you.

  • Home Medical Equipment

    Burke's Main Street Pharmacy is your single source for medical equipment and supplies.

  • Beach Wheelchair

    Let us make your trip to the beach easier.

  • Diabetes Specialized Care Center

    Have your diabetes needs covered in one place.

    Your type of diabetes is unique to you.  That is why our pharmacists offer specialized care and individualized treatment plans to help you simplify your diabetes...

  • Immunization Specialized Care Center

    Your vaccination destination.

    Our immunizing pharmacists are certified to administer vaccines with comfort and professionalism.

  • The Sweet Spot and Healthy Heart

    We find it imperative to assist our customers with information regarding their well being. We hold FREE classes on how to approach certain health issues.

Prescription Refills

Have your prescription refilled with just a few short clicks!

Monthly Specials

Keep your health in mind this holiday season!

Keep your health in mind this holiday season!

Our pharmacy is ready to help you prepare for the holidays, be it coping with stress, getting over a cold, or even weight management!

In-Store Savings For December. Products not available at all locations.

  • Leader Echinacea Extract

    125 mg. Capsules, 90 ct. Compare & Save

    $5.49
  • Schiff Digestive Advantage

    Daily Probiotic Capsules, 30 ct. or Gummies, 45-60 ct.

    $13.99
  • Leader Ibuprofen

    Ibuprofen 200 mg. Tablets or Caplets, 100 ct. Compare to Advil
    200 mg. Tablets, 100 ct. Compare to Motrin

    $4.49
  • Aleve

    All Day Strong Pain Reliever 220 mg. Caplets, Gelcaps or Tablets, 40-50 ct.

    $5.99

Events Calendar