Welcome to Burke's Main Street Pharmacy

Serving Hilton Head Island and Bluffton, South Carolina

How can we help you today?

Burke’s Main Street Pharmacy is here to help both local residents and visitors to Hilton Head Island look and feel their best. Our certified pharmacists are ready to help with your pharmacy and compounding needs. We can also help you find the medical equipment you need for daily life or to ensure your vacation to Hilton Head Island is the best it can be.

If you have any questions regarding our pharmacy services or medical equipment, please don’t hesitate to contact us!

Ancillary  Pharmacy
img: Specialty Pharmacy Services

Medical  Equipment
img: Medical Equipment

Customer Care
img: Customer Care

Recent Facebook Activity

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    Today marks the 30th anniversary of the opening of Burke's Pharmacy! Thanks to all our wonderful customers, staff, and community over the years.

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    If you still have questions, don't hesitate to ask a member of our friendly, expert staff!

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    Who knew retirement could be this comfy?

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